The most commonly used statin is Cataflam (rosuvastatin) (Furosemide (Elvartin)) (Tablet, Ora-Ventis, GSK). It’s a combination of two drugs. It is a well-tolerated drug with a relatively fast onset of action in the first week and an average duration of action of around 2 weeks. The recommended starting dose for most patients is 20 mg once a day and 20 mg twice a day. However, for those who are experiencing liver problems, a lower dose may be necessary to reduce side effects. The drug is only available by prescription, so you can only buy from registered pharmacies. This medicine can be used to treat other conditions in addition to cholesterol.

Tablets:Rosuvastatin is used for high cholesterol (LDL) cholesterol. It is a lipid-lowering drug that blocks an enzyme (Lipid-Enzymatic) that makes cholesterol from fatty substances. Rosuvastatin works by blocking the actions of an enzyme that makes cholesterol. As a result, you will see changes in your blood lipid profiles. This is a common side effect of statins, so you may experience other side effects such as weight gain, heart problems or liver problems. You should not take this medicine if you also take a blood thinner such as warfarin (Coumadin).

As with other cholesterol-lowering drugs, statin use should be individualized according to your individual risk factors and your medical history. Always follow your doctor’s instructions. For certain patients, taking statins at the same time each day will help prevent complications such as liver damage and heart failure.

It is important to follow your doctor’s instructions carefully. The starting dose of rosuvastatin is 20 mg once a day and 20 mg twice a day. It is recommended to start with the lowest effective dose for your individual risk factors. For high-risk patients, a lower dose of 20 mg once a day may be sufficient. If you have liver problems, your doctor may increase the dose to 40 mg once a day. The dose you take will depend on the severity of the problem and how much the patient wants to take.

Statins should not be taken with alcohol. It is important to let your doctor know that you are taking statins to prevent any serious side effects. They can also lower the dose of statins you take and may reduce the risk of side effects. This information is for guidance only and is not a substitute for personal medical advice. If you have any questions about this information, talk to your doctor.

https://www.gov.nasa.gov/publications/crestor-sales-in-ada/nasa-02000822/https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4070942/https://www.ncbi.nlm.nih.gov/pmc/articles/PMC44007605/https://www. OSP.org/drugs/furosemide-furosemide-tablet-tablet-side-effects-online-prescribing/OSP.org/drugs/cholesterol-drug-crestor-tablet-side-effects-online-prescribing/

See also:

*Corresponding author: Jessica Leffler, MS, PharmD, 801 E. Porter St, Office of Public Affairs, F. C. 5th St, Portage, NY 11003.

This document containsillustrates the most commonly used statins and is intended for informational purposes only. It is not a substitute for medical advice, diagnosis or treatment. Always seek the advice of your physician or other qualified health provider with any questions or concerns regarding a doctor-patient relationship.

AstraZeneca's cholesterol drug Crestor, marketed under the brand name Cholesterol-Reducer Lipid, is being sued for $10 billion for causing severe health risks associated with its use. The case was brought by the US Food and Drug Administration, and its lead plaintiff, the plaintiffs in a class action in the Northern District of Florida, alleging that AstraZeneca's conduct was an intentional use of a drug that was marketed under the name Crestor.

The company, which has been named as a defendant in the class action, is seeking $1 billion in damages from Crestor, as well as from the plaintiffs in the class and the drug's manufacturer, Apotex. The suit is based on the theory that Crestor caused serious health risks that were not listed on the label and are not considered adequate warnings to be given to patients who may have been adversely affected by the drug's use. The case is being captioned "Patient's Compensation Litigation" by the plaintiffs.

In January 2010, the US Food and Drug Administration granted the AstraZeneca class action, and the company filed a second application for class certification in April 2011. On June 11, 2011, the court denied class certification.

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The case was brought by AstraZeneca, its leading manufacturer of Crestor, against a number of drug manufacturers and distributors. The company has been accused of manufacturing and marketing the drug under the name of Crestor and had been linked to allegations that it has caused significant health risks associated with Crestor.

The complaint alleged that the drug had been used in an unsafe manner and that the manufacturer was aware of these risks, but that the company failed to adequately warn of these risks. The complaint also alleged that AstraZeneca knew or should have known of the risks associated with the drug before the FDA approved it in 2010. AstraZeneca did not disclose the risk to patients or to other companies. The complaint alleged that the company knew or should have known about the risks that it had identified in the warning statements but failed to disclose them to patients.

In April 2011, the court denied class certification on the basis that the complaint was based on allegations of a false and misleading statement and a mischaracterization of a warning. The court also declined to dismiss the matter on the basis that the allegations did not state a cause of action.

In February 2012, a jury trial in the case was conducted in the Northern District of Florida. The trial was also scheduled to begin in Philadelphia on June 27, 2012, and was to begin in Orlando, Florida, on June 28, 2012.

The case began on August 23, 2012. The case was being consolidated with another class action brought by a class action brought by AstraZeneca. The class includes both AstraZeneca and its leading drug company, AbbVie, which has been accused of causing serious health risks in a number of cases.

The class included AstraZeneca and AbbVie, the leading drug companies in the world, and other class action claimants, including:

AstraZeneca's case began on June 11, 2012.

The case was brought by a class plaintiff, the individual class representatives, the pharmaceutical companies and the class-action lawyers who represented the individual class representatives. The class consisted of AstraZeneca, AbbVie, and its leading drug company, AbbVie, which has been accused of causing serious health risks in a number of cases. The class included AstraZeneca, AstraZeneca and AbbVie, the leading drug companies in the world, and other class action claimants, including:

The individual class representatives were represented by a class-member panel and a panel of doctors, nurses, pharmacists and other professionals.

The individual class representatives and the pharmaceutical companies were represented by a panel of doctors, nurses, pharmacists and other professionals.

The class plaintiffs' representative, Dr. Robert L. Johnson, was represented by a panel of doctors, nurse practitioners, pharmacists and other professionals. The class representatives, Dr. John E. Johnson, an individual class member, and Dr. Richard J. Kneers, an individual class member, were represented by a panel of doctors, nurse practitioners, pharmacists and other professionals. The individual class representatives and the pharmaceutical companies were represented by a panel of doctors, nurse practitioners, pharmacists and other professionals.

Indications

In patients with primary hypercholesterolaemia, Crestor is indicated in combination with fibrates for the treatment of primary hypercholesterolaemia and reduction of total cholesterol and LDL cholesterol levels in patients with primary hypercholesterolaemia.

In patients with mixed dyslipidaemia, Crestor is indicated in combination with fibrates in order to reduce the risk of hypercholesterolaemia. In patients with mixed dyslipidaemia, Crestor is indicated in combination with fibrates in order to reduce the risk of hypercholesterolaemia and decrease the total cholesterol levels.

Adult Dose

The adult dose is 50 mg divided in three times a day. The dose should be increased by 5 mg every 2 days. The dose should be maintained for 5 years. The dose should be administered to patients with hypercholesterolaemia as the recommended dose in the treatment of primary hypercholesterolaemia.

Pediatric Dose

The dose of Crestor is 50 mg divided in three times a day.

Renal Dose

The renal clearance of Crestor is 0.6 mL/min/1.73 m2. The dosage should be maintained for 10 years. The dosage should be administered to patients with hypercholesterolaemia as the recommended dose in the treatment of primary hypercholesterolaemia.

Administration

May be taken with or without food.

Contraindications

Hypersensitivity to the active substance or to any of the excipients.

Special Populations

Renal Impairment.

Precautions

Patients with impaired renal function should be started on a dose of 50 mg three times a day. In case of the need for higher doses, it is recommended to increase the dose in increments of 5 mg every 2 days.

Pregnancy and Breastfeeding

The use of Crestor during pregnancy is not recommended due to its potential risk to the fetus. It is considered contraindicated during pregnancy and breastfeeding.

Interaction

Crestor may lead to hypertriglyceridaemia in some patients and increases serum levels of triglyceride in some patients. It is not recommended to monitor the levels of triglyceride in patients with dyslipidaemia because of potential serious adverse effects.

The use of Crestor during pregnancy is not recommended due to potential risk to the fetus.

Adverse Effects

Adverse effects of Crestor are:

• Diarrhea.
• Increased incidence of hypercholesterolaemia (men) and cholesterol effluvium.
• Reduced therapeutic response in patients with primary hypercholesterolaemia.

Storage

Store at a temperature not exceeding 30 °C in a dry place.

Roche CRESTOR CRESTOR (rosuverine) 10 mg/d Tablets

Warning

Use with caution in patients with severe hepatic impairment.

Roche CRESTOR (rosuverine) 5 mg/d Tablets

• Increased incidence of hypercholesterolaemia (men) and cholesterol effluvion.

Store at 20-25 °C and protected from light in a dry place.

Crestor (Rosuvastatin) Medication Information:

Crestor (rosuvastatin) is a medication commonly prescribed for the treatment of high cholesterol levels. It belongs to a class of drugs known as selective estrogen receptor modulators (SERMs). These medications work by reducing the binding of cholesterol-related hormones, such as aldosterone, to certain receptors in liver cells. This reduction in hormone levels helps to lower cholesterol in the blood. Lowering cholesterol can reduce the risk of heart disease and other cardiovascular problems. Crestor is often used in combination with other cholesterol-lowering medications to reduce cholesterol levels. It is important to follow a written dosage and safety plan when taking Crestor.

Common Side Effects:

Some side effects of Crestor may include:

• Headache
• Diarrhea
• Upset stomach
• Bloating
• Diarrhea with extreme hunger
• Heartburn
• Low blood pressure
• Low testosterone levels
• Rarely, muscle pain or weakness may occur. If you experience any of the following, seek medical attention immediately: muscle pain that does not go away, severe weakness that may be affecting daily functioning, feeling or being more depressed, confusion, memory problems, hallucinations, difficulty following movements, or difficulty understanding, disorientation, or dizziness.

How to Use:

• Take the medication at the same time each day.
• It is important to maintain a consistent daily dosage and follow your healthcare provider’s instructions. Take the medication with a full glass of water unless your doctor or pharmacist has advised you to avoid excessive alcohol consumption.
• It is important to maintain a balanced diet and regular exercise routine while taking Crestor, especially during the middle of the night.
• If you miss a dose of the medication, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take a double dose to make up for a missed dose.

Read this drug information patient information package to better understand Crestor dosage and side effects. It also provides more information about the medication’s uses, dosage forms, potential side effects, precautions and interactions with other drugs. CRESTOR Patient Information.

Crestor (Rosuvastatin) Warnings:

Crestor should not be taken by individuals who are hypersensitive or allergic to it or those mentioned above.

• Do not take Crestor if you are pregnant, planning to become pregnant, or breastfeeding without consulting your doctor.
• If you have any of the following conditions, avoid taking Crestor.
• Kidney problems, including kidney damage
• Liver disease, including severe liver failure
• Liver transplant problems
• Pregnancy
• Uncontrolled high or low blood pressure
• Breast feeding

If you are pregnant or breast-feeding, ask your doctor about Crestor dosage and side effects.

CRESTOR (Rosuvastatin) Interactions:

Interactions With Other Drugs:

• Corticosteroids may lower cholesterol levels, so you may need to take Crestor if you are at risk of high cholesterol or low blood pressure.
• Lithium may increase the risk of allergic reactions, cardiovascular problems, and kidney problems.
• Other cholesterol-lowering medications may affect how CRESTOR works.
• Certain drugs can increase the risk of liver problems or cardiovascular problems, so ask your doctor or pharmacist if you are at risk or take any other risk factors.

Drug Interactions:

• Corticosteroids may reduce the absorption of certain cholesterol-lowering medications. If you are taking a supplement with Crestor, you may be advised to take the supplement at the same time as CRESTOR.